Inter-laboratory evaluation demonstrates assay reproducibility in biodosimetry, suggesting broader radiation exposure applications.
These findings demonstrate that inter-laboratory reproducibility of γH2AX/53BP1-based biodosimetry is achieved primarily through disciplined workflow harmonization rather than through pharmacological enhancement. By reinforcing assay reproducibility and biological consistency, this work supports the translational applicability of IRIF-based biodosimetry for broader application in radiation exposure assessment.
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Zastko et al. (2026) studied this question.
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