Key result
LBBP appears feasible and safe for treating symptomatic bradycardia in nonagenarians.
Why the study?
Is left bundle branch pacing feasible and safe in nonagenarians with symptomatic bradycardia?
Observational (n=8)
No
Is left bundle branch pacing feasible and safe in nonagenarians with symptomatic bradycardia?
Left bundle branch pacing appears to be a feasible and safe physiological pacing strategy in frail nonagenarians with symptomatic bradycardia, demonstrating stable short-term parameters without complications.
Answers are grounded in this paper and cite their sources.
May expand physiological pacing options for nonagenarians with symptomatic bradycardia; extends LBBP evidence but remains hypothesis-generating pending RCTs.
BACKGROUND: Left bundle branch pacing (LBBP) is emerging as a physiological pacing strategy. However, data on its feasibility and safety in nonagenarians (≥90 years) with symptomatic bradycardia are limited. This study aims to evaluate the outcomes of LBBP in this frail, high-risk population. METHODS: A retrospective analysis was conducted on 8 patients aged 90 and older who underwent LBBP between December 2023 and December 2024. Procedural outcomes, complications, and pacing parameters were assessed. RESULTS: LBBP was successfully performed in 8 patients (mean age 93 ± 2 years, mean Clinical Frailty Score 5). The pacing indications included atrioventricular block and sinus node dysfunction. The mean left ventricular activation time was 75 ± 8 ms. At a median follow-up of 6 weeks, pacing parameters remained stable with no evidence of lead displacement, haematoma, or infection. There were no immediate procedural complications. CONCLUSIONS: LBBP appears to be a feasible and safe physiological pacing strategy in nonagenarians with symptomatic bradycardia. Further studies are needed to confirm the long-term outcomes of LBBP in elderly patients.
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Khaw et al. (2026) conducted an observational in Symptomatic bradycardia (n=8). Left bundle branch pacing was evaluated on Procedural outcomes, complications, and pacing parameters. Left bundle branch pacing was successfully performed in 8 nonagenarians with symptomatic bradycardia, with no immediate procedural complications and stable pacing parameters at 6 weeks.
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