Why the study?
Does omeprazole reduce upper gastrointestinal bleeding in patients with coronary artery disease receiving aspirin and clopidogrel?
Does omeprazole reduce upper gastrointestinal bleeding in patients with coronary artery disease receiving aspirin and clopidogrel?
Prophylactic omeprazole reduces upper gastrointestinal bleeding in CAD patients on dual antiplatelet therapy without apparent adverse cardiovascular interactions.
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May support PPI prophylaxis on DAPT without apparent harm; leaves open confirmation of no clopidogrel interaction in larger trials.
Bhatt et al. (2010) studied this question.
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