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March 3, 2026Scientific ReportsOpen Access

Effectiveness of endovenous ablation techniques and surgery for great saphenous vein incompetence: a comprehensive meta-analysis of randomized controlled trials

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Authors

CSCeren SayarerMAMehmet Emin ArayiciTGTuğra Gençpinar

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Overview

Meta-analysis compares the effectiveness and safety of endovenous techniques and surgery in treating GSV incompetence, indicating similar outcomes.

Key Points

  • This research aims to compare the effectiveness and safety of various treatments for great saphenous vein incompetence.
  • Meta-analysis of randomized controlled trials
  • Review of databases including PubMed, Embase, and Cochrane Library
  • Assessment of complications and patient-reported outcomes
  • Risk of bias evaluated across included studies
  • Use of random- and fixed-effects models for data analysis
  • No significant difference in occlusion rates between EVLA and surgery (RR = 0.98)
  • EVLA showed fewer nerve injuries than surgery (RR = 0.47, p < 0.01)
  • RFA showed no significant differences in occlusion rates compared to surgery (RR = 1.00)
  • EVSA was non-inferior to EVLA with respect to outcomes
  • UGFS had inferior long-term durability compared to other methods

Cite This Study

Sayarer et al. (2026) studied this question.

synapsesocial.com/papers/69a67e0ef353c071a6f09ee8https://doi.org/10.1038/s41598-026-42413-2
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