Impact of offering blood-based testing alongside existing modalities for colorectal cancer screening among those who previously declined screening: an economic evaluation.

Key Points

• This research aims to assess the economic impact of adding blood-based tests to existing colorectal cancer screening approaches for individuals who have not participated in screening.
• Utilized a simulation model to integrate data from recent clinical trials.
• Evaluated cost-effectiveness of blood-based tests compared to traditional screening methods.
• Focused on the unscreened population for colorectal cancer.
• Blood-based tests could significantly reduce colorectal cancer deaths in the target population.
• Cost-effective strategies identified for increasing screening participation and outcomes.
• Potential to avert more CRC deaths compared to traditional screening alone.