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Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements | Synapse
March 3, 2026
Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements
MD
Menno Van Damme
Ghent University Hospital
SS
Sanne Stegen
Ghent University Hospital
BS
Bram Steenwinckel
Ghent University Hospital
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Key Points
Exercise promotes deceleration in epigenetic age, enhancing overall health and fitness levels.
Participants showed a significant improvement in cardiorespiratory fitness due to regular exercise habits, enhancing biological resilience.
Assessment using molecular pathways related to epigenetic age and cardiorespiratory fitness reveals strong correlations.
Highlights the potential for lifestyle interventions to influence biological aging and overall health outcomes.
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Damme et al. (Sat,) studied this question.
synapsesocial.com/papers/69a759e7c6e9836116a1f4a6
https://doi.org/https://doi.org/10.1007/s11357-025-02076-9
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