Quality of life in recurrent acute pancreatitis and chronic pancreatitis: A prospective cross-sectional comparative bicentric study

Amith Viswanath; Nicholas Vijay Rao; Megha Sharma; Rajesh S; Yugalakshmi A; Sumathy. J Sumathy. J; Gauri Kumbhar; Ajith Thomas; Reuben Thomas Kurien; Jayanta Samanta; Sudipta Dhar Chowdhury

doi:10.1007/s12664-025-01904-2

January 17, 2026Indian Journal of Gastroenterology

Quality of life in recurrent acute pancreatitis and chronic pancreatitis: A prospective cross-sectional comparative bicentric study

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Why the study?

Data comparing quality of life between chronic pancreatitis and recurrent acute pancreatitis remained limited, particularly in Indian populations.

Does quality of life differ between patients with chronic pancreatitis, recurrent acute pancreatitis, and healthy controls?

Key Points

Quality of life varies significantly between patients with recurrent acute pancreatitis and chronic pancreatitis.
The study observed a measurable difference in quality of life scores among the two groups over a defined period.
Prospective cross-sectional analysis involved detailed assessments across multiple healthcare centers to ensure accuracy.
This highlights the need for tailored interventions in managing symptoms and improving the quality of life in these patients.

Structured PICO

Does quality of life differ between patients with chronic pancreatitis, recurrent acute pancreatitis, and healthy controls?

P

Population

216 participants: 54 chronic pancreatitis (CP) patients (mean age 26.8 ± 9.4 years, 59.3% male), 54 recurrent acute pancreatitis (RAP) patients (mean age 28.4 ± 10.4 years, 79.6% male) and 108 age-matched healthy controls.

C

Comparator

Healthy controls and comparison between CP and RAP groups

O

Outcome

Quality of life evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30)patient reported

Implication

Chronic pancreatitis is associated with significant quality of life impairment compared to recurrent acute pancreatitis, highlighting a critical window for intervention before disease progression.

Discussion

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Cite This Study

Viswanath et al. (2026) studied this question.

synapsesocial.com/papers/69a759f7c6e9836116a1f64c https://doi.org/10.1007/s12664-025-01904-2

View Full Paper

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Quality of life in recurrent acute pancreatitis and chronic pancreatitis: A prospective cross-sectional comparative bicentric study

Key Points

Structured PICO

Implication

Discussion

Cite This Study

Quality of life in recurrent acute pancreatitis and chronic pancreatitis: A prospective cross-sectional comparative bicentric study

Key Points

Structured PICO

Implication

Discussion

Cite This Study

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