Methane Sulphonic Anhydride Enabled an Efficient and Straightforward Protocol for the Synthesis of Hydroxamic Acid Derivatives and Evaluation of their In-silico ADME Properties

Key Points

• Hydroxamic acid derivatives were synthesized efficiently using methane sulphonic anhydride, achieving streamlined processes.
• Key evaluation included in-silico assessments of ADME properties for these derivatives, ensuring thorough analysis.
• The synthesis employed a straightforward protocol, enhancing accessibility for further applications in chemical research.
• Overall, the findings highlight the potential for developing effective methodologies in organic synthesis and drug design.