March 3, 2026Journal of Veterinary Internal Medicine0 citationsOpen Access

Intrapulmonary arteriovenous anastomoses in healthy dogs assessed using saline contrast echocardiography and response to oxygen therapy

KCKyumin ChoJeonbuk National University SKSung-Soo KimThe Schwarzman Animal Medical Center KLKichang LeeJeonbuk National University

Key Points

Delayed microbubble appearance in healthy dogs indicates potential shunting mechanisms.
Oxygen supplementation significantly decreases intrapulmonary arteriovenous anastomosis flow in subjects.
Assessment using saline contrast echocardiography reveals insights into cardiovascular physiology.
Highlights a dynamic relationship between inspired oxygen levels and pulmonary shunt regulation.

Abstract

Intrapulmonary arteriovenous anastomoses are common in clinically healthy dogs and may cause delayed left ventricular microbubble appearance during saline contrast echocardiography, potentially mimicking intracardiac right-to-left shunts. Oxygen supplementation significantly decreased IPAVA flow, suggesting that these physiological shunts may be dynamically regulated by inspired oxygen levels.

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Cho et al. (Thu,) studied this question.

synapsesocial.com/papers/69a75a7ac6e9836116a20594 https://doi.org/https://doi.org/10.1093/jvimsj/aalaf076

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