Circularization of 23S rRNA but not 16S rRNA within archaeal ribosomes

Ling-Dong Shi; Petar I. Penev; Amos J. Nissley; Dipti D. Nayak; Rohan Sachdeva; Jamie H. D. Cate; Jillian F. Banfield

doi:10.1186/s13059-025-03903-0

January 27, 2026Genome biologyOpen Access

Circularization of 23S rRNA but not 16S rRNA within archaeal ribosomes

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Key Points

Findings uncover critical differences in the circularization of 23S rRNA compared to 16S rRNA, highlighting unique processing events.
Key evidence shows that the formation of functional ribosomal molecules relies on diverse rRNA maturation pathways.
Observational analysis focused on the variation in rRNA configuration within archaeal ribosomes, noting crucial aspects of their structure.
These findings emphasize the need for more research on rRNA processing, which could reshape our understanding of archaeal biology.

Implication

Analysis reveals distinct processing differences in rRNA types within archaeal ribosomes, suggesting implications for ribosomal function.

Abstract

Our findings uncover unexpected variations in the processing required to generate mature rRNAs and the conformation of functional molecules in archaeal ribosomes.

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Cite This Study

Shi et al. (2026) studied this question.

synapsesocial.com/papers/69a75abdc6e9836116a20ef9 https://doi.org/10.1186/s13059-025-03903-0

View Full Paper

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Circularization of 23S rRNA but not 16S rRNA within archaeal ribosomes

Key Points

Implication

Abstract

Discussion

Cite This Study

Circularization of 23S rRNA but not 16S rRNA within archaeal ribosomes

Key Points

Implication

Abstract

Discussion

Cite This Study

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