Racial, ethnic and sex‐specific mechanisms of obstructive sleep apnea and Alzheimer's disease risk

Komal Patel Murali; Joshua Gills; Arlener Turner; Anthony Briggs; Mark Bernard; Elena Valkanova; Alfred K. Mbah; Ogie Queen Umasabor‐Bubu; Glenna Brewster; Zainab Osakwe; Natasha Williams; Clemma Muller; Dayna A. Johnson; Chinedu T. Udeh‐Momoh; Olugbenga Ogedegbe; Indu Ayappa; Ricardo Osorio; Girardin Jean‐Louis; Alberto R. Ramos; Omonigho Michael Bubu

doi:10.1002/alz.71144

Key Points

Hypoxia, fragmentation, and duration contribute to variations in Alzheimer's disease risk across racial and ethnic groups.
Research shows significant differences in risk mechanisms, indicating a need for tailored approaches in treatment.
Analysis highlights the interplay between obstructive sleep apnea and Alzheimer's disease risk in different demographics.
This may enable more effective screening methods to identify at-risk groups based on sex and ethnicity.

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Implication

Observational analysis reveals racial and sex-specific mechanisms affecting Alzheimer's disease risk via sleep apnea, suggesting targeted interventions are necessary.

Abstract

Hypoxia, fragmentation, and duration may underlie racial-, ethnic-, and sex-specific effects of AD risk.

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Cite This Study

Murali et al. (2026) studied this question.

synapsesocial.com/papers/69a75ae2c6e9836116a214d9 https://doi.org/10.1002/alz.71144

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Racial, ethnic and sex‐specific mechanisms of obstructive sleep apnea and Alzheimer's disease risk

Key Points

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Implication

Abstract

Discussion

Cite This Study

Racial, ethnic and sex‐specific mechanisms of obstructive sleep apnea and Alzheimer's disease risk

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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