Cytological Features of Gangliocytic Paraganglioma Occurring in the Duodenum

Key Points

Gangliocytic paraganglioma presents with distinct cytological features, highlighting its diagnosis.
The specimen analysis included three cell types: epithelioid, spindle, and ganglion-like cells.
Assessment used endoscopic ultrasound-guided fine needle aspiration (EUS-FNAC) for accurate sampling.
Understanding these features is crucial for differentiating from similar tumors like NET and GIST.

Abstract

Gangliocytic paraganglioma (GP) is a rare tumor that predominantly occurs in the duodenum. We report a case of GP in a man in his 70s. The specimen obtained by EUS-FNAC revealed three cell populations: epithelioid cells, spindle cells, and ganglion-like cells, similar to those seen in NET and paraganglioma. While NET and GIST are considered differential diagnoses, the cytological features of GP have been reported, but the number of such reports is limited. In this paper, we report a case of GP with a comparison of cytological and histological findings.

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Cite This Study

Kamio et al. (Tue,) studied this question.

synapsesocial.com/papers/69a75aefc6e9836116a2168a https://doi.org/https://doi.org/10.1002/dc.70085

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