Clinical exome sequencing identifies novel gene variants associated with ischemic stroke in the Saudi Tabuk population

Key Points

• Ischemic stroke risk is associated with 11 novel gene variants, linked specifically to the Saudi population.
• The study identified several known polymorphisms relevant to ischemic stroke, providing context to genetic susceptibility.
• Case-control analysis was employed to identify genetic associations with ischemic stroke in Saudi patients.
• These findings suggest further functional validation and research into population-specific genetic factors.