Polymeric micro- and nanoparticle release from cardiopulmonary bypass and extracorporeal membrane oxygenation circuits

Key Points

• Micro- and nanoparticles (MNPs) are released from cardiopulmonary bypass (CPB) and ECMO circuits over time, leading to varying health effects.
• Over the use period, the total number of MNPs in circuits significantly increases, suggesting growing exposure risks for patients.
• Assessment of MNPs from CPB and ECMO circuits provides insights into their potential health effects and emphasizes the need for further investigation.
• Understanding the implications of MNP release could inform safer practices for medical circuit usage and patient outcomes.