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January 27, 2026Journal of Neural Transmission

Obesity-related RNA m6A demethylase gene FTO rs1421085 is associated with neuroticism in a longitudinal birth cohort study

Triin Kurrikoff Diva Eensoo Jaanus Harro

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Key Points

Neuroticism is linked to the FTO rs1421085 genotype, implying genetic factors may influence personality traits.
Participants were followed over a significant time, allowing for the observation of changes in neuroticism related to genetic variations.
Analysis was conducted on data from a longitudinal birth cohort to identify connections between genotype and psychological outcomes.
Findings highlight the need for further research on genetic influences on personality, particularly regarding mental health.

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Implication

Longitudinal analysis reveals a link between FTO rs1421085 genotype and neuroticism, suggesting further exploration needed.

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Cite This Study

Kurrikoff et al. (2026) studied this question.

synapsesocial.com/papers/69a75b58c6e9836116a22876 https://doi.org/10.1007/s00702-026-03108-0

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