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March 3, 2026Journal of Affective Disorders7 citationsOpen Access

Intolerance of uncertainty and depression in children and adolescents: Systematic review and meta-analysis

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LMLeo MaresMFMathew Fuller

Key Points

  • Children and adolescents show a medium-strong association between intolerance of uncertainty and depression symptoms.
  • It is important to consider child-friendly measures when assessing intolerance of uncertainty in youth populations.
  • The analysis highlights the need for longitudinal and experimental designs to strengthen the evidence base.
  • Future research should emphasize the selection of appropriate assessment tools to avoid overestimating associations.

Abstract

There is a medium-strong association between IU and depression symptoms in children and adolescents. However, it may be overestimated by the use of IU measures that are not child-friendly. Future research can further extend the evidence-base through careful measure selection, as well as longitudinal and experimental designs.

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Cite This Study

Mares et al. (2026) studied this question.

synapsesocial.com/papers/69a75b67c6e9836116a22abbhttps://doi.org/10.1016/j.jad.2026.121288
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