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March 3, 2026Epilepsia2 citationsOpen Access

Freedon study: Real‐life outcomes of cenobamate in different lines of treatment

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VVV VillanuevaJSJosé María SerratosaAFAlejandro Fernández‐Cabrera

Key Points

  • Cenobamate showed high effectiveness over 1 year in patients previously tried on 2-6 ASMs, confirming its real-world application.
  • Patients using cenobamate earlier in their treatment history experienced better outcomes than those who started it later.
  • This observational analysis highlights cenobamate's well-tolerated profile, supporting its use in diverse treatment lines.
  • Improved outcomes suggest that timely intervention with cenobamate may enhance management in epilepsy treatment.

Abstract

Cenobamate was effective and well tolerated in patients who had tried 2-6 prior ASMs in a real-world setting. High effectiveness was confirmed at 1 year, with better outcomes in earlier users.

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Cite This Study

Villanueva et al. (2026) studied this question.

synapsesocial.com/papers/69a75bbac6e9836116a2395fhttps://doi.org/10.1002/epi.70106
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