Associations between obesity, metabolic syndrome and glaucoma in the National Institutes of Health ‘All of Us’ research programme | Synapse
March 3, 2026
Associations between obesity, metabolic syndrome and glaucoma in the National Institutes of Health ‘All of Us’ research programme
Key Points
Higher BMI and increased waist circumference correlate with a lower likelihood of glaucoma, indicating a complex relationship between obesity and ocular health.
Metabolic syndrome shows a contrasting association, being linked to an increased likelihood of developing glaucoma in participants enrolled in the research programme.
The analysis utilized data from the National Institutes of Health 'All of Us' initiative, which collects extensive health data across diverse groups.
Further exploration is needed to understand the mechanisms behind these associations and their implications for preventing glaucoma.
Abstract
In AoU, higher BMI and increased WC were associated with a lower likelihood of glaucoma, while MetS was associated with an increased likelihood of glaucoma.