March 3, 2026Open Access

Mechanical Thrombectomy in the Management of Acute Ischemic Stroke Secondary to Calcified Cerebral Emboli: a Systematic Review

Key Points

Lower recanalisation rates and poor functional outcomes are noted in acute ischemic stroke cases related to calcified cerebral emboli.
Findings from 14 studies show that mechanical thrombectomy's effectiveness is limited for these specific scenarios.
Observational studies dominate the evidence base, raising concerns about the reliability of the conclusions drawn.
The implications of poor outcomes highlight the need for careful consideration in treatment plans for acute ischemic stroke.

Abstract

The available evidence from 14 studies elucidated poor recanalisation rates and functional outcomes when MT was used in the management of AIS secondary to CCE. However, the available evidence is primarily low-level evidence from observational studies, hence the conclusions should be interpreted with caution.

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Cite This Study

Pavic et al. (Wed,) studied this question.

synapsesocial.com/papers/69a75c1ec6e9836116a2499a https://doi.org/https://doi.org/10.1007/s00062-025-01611-7

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