Primary thymic mucoepidermoid carcinoma with positive MAML2 gene rearrangement: a case report

Yongbei Luo; Chen Xu; Qiangwei Huang; Lei Fan; Yu Deng; Qing Ai; Yalei Zhang; Yuan Qiu

doi:10.21037/gs-2025-1-591

January 1, 2026Gland SurgeryOpen Access

Primary thymic mucoepidermoid carcinoma with positive MAML2 gene rearrangement: a case report

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Key Points

Mucoepidermoid carcinoma shows a positive MAML2 gene rearrangement, indicating potentially better outcomes.
The detailed pathology and molecular testing led to the diagnosis of this uncommon thymic carcinoma type.
This case emphasizes the role of MAML2 in prognosis, pushing for more research to clarify treatment strategies.
Understanding the pathogenesis may guide future therapeutic approaches for thymic mucoepidermoid carcinoma.

Implication

Case report details a rare thymic tumor with MAML2 gene rearrangement, suggesting improved prognosis.

Abstract

This report details a rare case of thymic MEC. The diagnosis required pathology and molecular testing. MAML2 rearrangement suggests a better prognosis; further research is needed to elucidate its pathogenesis and improve its treatment.

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Cite This Study

Luo et al. (2026) studied this question.

synapsesocial.com/papers/69a75cacc6e9836116a25bd6 https://doi.org/10.21037/gs-2025-1-591

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Primary thymic mucoepidermoid carcinoma with positive MAML2 gene rearrangement: a case report

Key Points

Implication

Abstract

Discussion

Cite This Study

Primary thymic mucoepidermoid carcinoma with positive MAML2 gene rearrangement: a case report

Key Points

Implication

Abstract

Discussion

Cite This Study

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Keep reading

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