Observational analysis reveals CREM's prognostic potential as a biomarker in thyroid carcinoma, suggesting its role in immune regulation.
CREM may function as a tumor suppressor and immune regulator in THCA. Its expression correlates with reduced immune infiltration and improved clinical outcomes, suggesting its potential as a prognostic biomarker and therapeutic target. Further experimental validation is warranted.
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Ling et al. (2026) studied this question.
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