Plasma proteome mendelian randomization and network pharmacology reveal therapeutic targets for thyroid disorders

Key Points

• Therapeutic targets emerge from network pharmacology for thyroid disorders, offering new treatment avenues.
• Key findings suggest that specific biomarkers associated with thyroid disorders can guide therapeutic strategies.
• Analysis uses mendelian randomization to establish relationships between genetic variants and thyroid function.
• This work highlights the importance of plasma proteome analysis in understanding thyroid disorders and guiding treatments.