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Cenobamate’s effect on mood and seizure frequency | Synapse
March 3, 2026
Open Access
Cenobamate’s effect on mood and seizure frequency
MK
Mert Karatas
AY
Alperan Yavuz
BN
Blake Newman
University of Utah
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Key Points
Mood improvement was observed alongside a decrease in seizure frequency with cenobamate treatment.
The study reported an average seizure frequency reduction of 40% over three months in participants treated with cenobamate.
Analysis involved assessing both mood and seizure data from clinical evaluations, highlighting the dual benefit of the intervention.
Further validation of cenobamate's effects is needed across diverse patient populations to confirm findings.
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Karatas et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75dbfc6e9836116a27fa5
https://doi.org/https://doi.org/10.1016/j.yebeh.2026.110913