Polymorphism and transcriptional regulation of GSTP1 in cancer and other human diseases

Key Points

• Polymorphism in GSTP1 is linked to cancer risk and progression, emphasizing its role as a potential biomarker.
• Notable findings indicate that certain genetic variants in GSTP1 can affect transcriptional regulation in various diseases.
• Analysis focused on various disease contexts, including cancer, revealing the significance of GSTP1 polymorphism across a wide spectrum.
• Further studies are needed to validate these findings in larger, diverse populations, enhancing understanding of GSTP1's role.