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January 1, 2026Spanish Journal of Psychiatry and Mental Health

Depression phenotypes informed by the RDoC framework using the Patient Health Questionnaire-9: A retrospective study in Peru

Javier A. Flores-Cohaila Jeff Huarcaya-Victoria Cesar Copaja-Corzo

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Key Points

Identifying depression phenotypes enhances understanding of mental health conditions across populations, especially in Peru.
The study reveals insights into varying depression types informed by the RDoC framework and assessed through the PHQ-9 scale.
Observational analysis leveraging data from the Patient Health Questionnaire-9 assesses depression characteristics retrospectively.
These findings suggest the need for tailored treatment strategies, emphasizing the importance of early identification based on phenotype.

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Implication

Retrospective study identifies depression phenotypes using RDoC framework with PHQ-9 in Peru, highlighting implications for diagnosis.

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Cite This Study

Flores-Cohaila et al. (2026) studied this question.

synapsesocial.com/papers/69a75dcfc6e9836116a280fc https://doi.org/10.1016/j.sjpmh.2025.11.007

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