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Targeting hORAI1-Mediated Calcium Influx in Triple-Negative Breast Cancer: A Computational Drug Discovery Approach | Synapse
March 3, 2026
Targeting hORAI1-Mediated Calcium Influx in Triple-Negative Breast Cancer: A Computational Drug Discovery Approach
SP
Sangavi Pandi
HN
Hemavathy Nagarajan
SS
Sneha Subramaniyan
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Key Points
Calcium influx targeting shows promise for triple-negative breast cancer therapies.
The computational drug discovery approach identifies specific interventions for hORAI1.
Molecular pathways linked to hORAI1 offer new insights for cancer treatments.
Findings imply that manipulating calcium levels may impact cancer progression.
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Pandi et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75dd4c6e9836116a28146
https://doi.org/https://doi.org/10.1007/s00232-025-00365-0