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Pharmacovigilance analysis reveals 19 drugs linked to male infertility, suggesting importance of pre-prescription counseling.
This pharmacovigilance study identified 19 high-risk drugs for male infertility across hormonal agents, antineoplastic drugs, and antidepressants. These findings underscore pre-prescription, risk-stratified fertility counseling for reproductive-age males, prioritizing sperm cryopreservation before chemotherapy and considering it selectively for 5α-reductase inhibitors, testosterone, or antidepressants.
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Gong et al. (2026) studied this question.
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