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March 3, 2026Neurosurgery Open0 citationsOpen Access

CyberKnife Stereotactic Radiosurgery for Vestibular Schwannomas: Systematic Review and Meta-Analysis of Long-Term Tumor Control and Hearing Preservation Outcomes

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NBNolan J. BrownZPZach PenningtonSPSaarang Patel

Key Points

  • High rates of tumor control were observed in patients undergoing cyberknife stereotactic radiosurgery.
  • Data indicates significant tumor control alongside hearing preservation for small vestibular schwannomas.
  • This systematic review included multiple studies evaluating long-term outcomes of cyberknife treatment.
  • Future studies should compare cyberknife with other radiosurgery methods, such as gamma knife.

Abstract

This systematic review and meta-analysis found that CKRS offers high rates of tumor control and hearing preservation in patients undergoing stereotactic radiosurgery for vestibular schwannomas. Current data suggest that CKRS is a reasonable, safe therapeutic option for patients with small tumors and preserved hearing. Further exploration in larger cohorts and direct comparison with GKRS is merited.

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Cite This Study

Brown et al. (2026) studied this question.

synapsesocial.com/papers/69a75e7fc6e9836116a29281https://doi.org/10.1227/neuprac.0000000000000202
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