Current and emerging maintenance strategies after stem cell transplantation in children and adolescents with acute leukemias

Key Points

• Maintenance therapy improves survival rates in pediatric patients with acute leukemia, particularly in those undergoing stem cell transplantation.
• Recent data suggests new protocols can enhance immunosuppression effectiveness while reducing toxicity in younger patients.
• Observational analysis across various healthcare centers identifies key strategies for effective post-transplant maintenance.
• Future research may enable more targeted maintenance therapies, optimizing long-term outcomes for children with acute leukemia.