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March 3, 2026Molecular Biology Reports0 citationsOpen Access

SUMOylation machinery protein, PIAS4 role in breast cancer cell proliferation and drug sensitivity

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MSMohammed A. M. SalihMSMohamed M. A. E. L. SalemMSMuhammad Ali Shahid

Key Points

  • PIAS4 plays a critical role in regulating breast cancer cell proliferation and drug sensitivity.
  • Inhibition of PIAS4 led to significant decreases in cell growth and alterations in drug response.
  • Analysis utilized breast cancer cell lines, examining their behavior in response to varying drug treatments.
  • These findings may highlight new therapeutic avenues for enhancing drug sensitivity in breast cancer.
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Cite This Study

Salih et al. (2026) studied this question.

synapsesocial.com/papers/69a75ea9c6e9836116a297bdhttps://doi.org/10.1007/s11033-025-11423-0
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