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Observational analysis reveals links between anti-CD320 autoantibodies and vitamin B12 deficiency in idiopathic myelopathy, suggesting diagnostic pathways.
ABCD is associated with a substantial proportion of IM. Screening for anti-CD320 followed by metabolic confirmation of a CNS-restricted B12 deficiency may be considered in the diagnostic evaluation of myelopathy.
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Pluvinage et al. (2026) studied this question.