Cystatin C Is a More Sensitive Marker of Renal Dysfunction in Children with Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy

Key Points

• Cystatin C effectively identifies renal dysfunction, improving detection in children with hematopoietic cell transplant.
• Key evidence highlights cystatin C sensitivity in renal assessment, surpassing traditional markers in 56 pediatric cases.
• Assessment through biomarker analysis enhances understanding of thrombotic microangiopathy related to renal impairment.
• Findings suggest monitoring cystatin C could lead to earlier intervention, impacting long-term transplant outcomes.