Effect of late-onset on multiple sclerosis phenotype and outcome: evidence from a multi-national registry

Key Points

• Late-onset multiple sclerosis significantly alters patient phenotype and clinical outcomes, impacting treatment strategies.
• The rate of disability progression in patients with late-onset multiple sclerosis highlights the long-term risks associated with this phenotype.
• Observational analysis across multiple countries utilized a comprehensive registry to track various disease outcomes related to late-onset.
• These findings underscore the need for targeted interventions for late-onset cases, emphasizing the distinct nature of this multiple sclerosis subtype.