Activation of donor-derived eosinophils during static storage contributes to primary graft dysfunction after lung transplantation

Key Points

• Primary graft dysfunction increases with activated donor-derived eosinophils after lung transplant.
• The study found eosinophil activation levels correlated with dysfunction rates in organ recipients.
• Analysis reveals a link between static storage conditions and activation of eosinophils from donors.
• Understanding these mechanisms may enhance outcomes for lung transplantation patients.