This article comments on a recent study by Guo et al demonstrating that pretraction-assisted endoscopic submucosal dissection (p-ESD) significantly improves treatment outcomes for rectal neuroendocrine tumors. Compared to conventional endoscopic submucosal dissection, p-ESD offers advantages such as shorter dissection time, higher R0 resection rates, and reduced incidence of complications. While acknowledging these encouraging findings, this study highlights key directions for future development: Elucidating the specific mechanisms of pretraction, establishing the generalizability of p-ESD through prospective multicenter studies, and validating its oncological efficacy through long-term follow-up. Addressing these issues is crucial for the broader application and standardization of p-ESD in clinical practice.
Dai et al. (Wed,) studied this question.