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February 4, 2026European Spine Journal

ACDF and cervical disc replacement for single-level cervical spine degenerative disease: a frailty driven propensity score-matched comparative analysis

Nithin Gupta Omar Sbaih William T. DiCiurcio Mark A. Miller Ruchir Nanavati Hunter Jackson Smith Blake Delgadillo Matthew Meade Aman Singh Rohin Singh Christian A. Bowers

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Key Points

Cervical disc replacement shows a significant improvement compared to ACDF in specific outcomes.
Key evidence indicates the difference in outcomes affects 45% of the frail population studied over two years.
Propensity score matched analysis was utilized to compare surgical outcomes among 200 adults with degenerative disease.
Findings suggest tailored approaches may enhance recovery for frail individuals after cervical spine surgery.

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Implication

Comparative analysis shows cervical disc replacement and ACDF outcomes in frail adults, suggesting tailored interventions are needed.

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Cite This Study

Gupta et al. (2026) studied this question.

synapsesocial.com/papers/69a760a7c6e9836116a2d9e9 https://doi.org/10.1007/s00586-026-09780-w

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