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Observational analysis reveals rising HR-HPV genotypes linked to cervical disease severity in Latvia, suggesting need for expanded genotyping.
HPV16 remained the most prevalent HR-HPV, while HPV18 decreased. Other HR-HPV genotypes (HPV 66/45/39/31/33) demonstrated an increase in prevalence. Cervical disease severity was linked to specific HR-HPV loads and the number infecting HR-HPVs. These findings highlight the need for extended HR-HPV genotyping with determination of viral load, and request more epidemiological studies analyzing historical and current samples.
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Sokolovska et al. (2026) studied this question.
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