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Hepatic Glucose Production by Glycophagy Is Controlled by the Small Gtpase Rab4b | Synapse
March 3, 2026
Hepatic Glucose Production by Glycophagy Is Controlled by the Small Gtpase Rab4b
JG
Jérôme Gilleron
DM
Dussot Marion
SS
Sihame Sabbane
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Key Points
Glycophagy significantly influences hepatic glucose production, aiding metabolic balance and efficiency.
Rab4B, a small GTPase, plays a central role in regulating glucose levels in the liver.
Findings indicate a strong link between glycophagy and metabolic regulation in hepatocytes.
These results highlight the potential of targeting Rab4B for metabolic interventions in glucose homeostasis.
Abstract
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Gilleron et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760e8c6e9836116a2e271