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March 3, 2026
Dual-readout aptasensor based on CRISPR/Cas12a and nanozyme for accurate detection of KIM-1 and its application in kidney transplant prognosis
LZ
Liping Zhao
ZL
Zhuoting Liu
GD
Guangpu Ding
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Key Points
Significant accuracy in KIM-1 detection supports better kidney transplant prognosis.
The aptasensor demonstrated a sensitivity of 0.5 ng/mL for KIM-1, enhancing early detection abilities.
Analysis combines the CRISPR/Cas12a system with a nanozyme approach for effective diagnostics.
This work provides a foundation for advanced kidney health monitoring; further clinical validation is encouraged.
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Zhao et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76107c6e9836116a2e8b4
https://doi.org/https://doi.org/10.1016/j.bios.2026.118533
Dual-readout aptasensor based on CRISPR/Cas12a and nanozyme for accurate detection of KIM-1 and its application in kidney transplant prognosis | Synapse