Polymorphonuclear myeloid-derived suppressor cells inhibit natural killer cell function in neuromyelitis optica spectrum disorder via the CD155-TIGIT axis | Synapse
March 3, 2026
Polymorphonuclear myeloid-derived suppressor cells inhibit natural killer cell function in neuromyelitis optica spectrum disorder via the CD155-TIGIT axis
Key Points
Natural killer cell function is significantly inhibited by polymorphonuclear myeloid-derived suppressor cells.
Inhibition through the CD155-TIGIT axis highlights a critical immune suppression mechanism.
The analysis focuses on neuromyelitis optica spectrum disorder to understand immune interactions.
These findings may guide future therapies targeting immune pathways for improved outcomes.