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Zha-Chong Shi-San-Wei Pill inhibits ferroptosis in cerebral ischemia via bioinformatics and experimental confirmation methods | Synapse
March 3, 2026
Zha-Chong Shi-San-Wei Pill inhibits ferroptosis in cerebral ischemia via bioinformatics and experimental confirmation methods
JS
Jinfeng Shang
WC
W Chen
WW
Wanting Wei
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Key Points
Ferroptosis reduction is linked to treatment with Zha-Chong Shi-San-Wei Pill in ischemic conditions.
Bioinformatics methods provided key insights into molecular pathways affected by the intervention.
Experimental confirmation involved testing the effects on ferroptosis in animal models of cerebral ischemia.
The findings may enable new strategies for treating ischemic brain injuries in clinical settings.
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Shang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a761ccc6e9836116a2fde7
https://doi.org/https://doi.org/10.1016/j.jep.2026.121402