⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

January 1, 2026American Journal of Cancer Research

Angiopoietin-like 4 deficiency upregulates macrophage function through the dysregulation of cell-intrinsic fatty acid metabolism [Retraction]

View Full Paper

Ask AI

Bookmark

Share

Key Points

Retraction notice formally withdraws the report linking angiopoietin-like 4 deficiency to upregulation of macrophage function, ending citation of its metabolic claims.
The notice for the retracted paper on fatty acid metabolism is accompanied by publisher metrics reporting 13 of 17 medical journals indexed officially in PubMed.
Evaluation of editorial records for studies on angiopoietin-like 4 shows 11 publisher journals indexed in Web of Science, with 2 titles possessing impact factors.

Design

Other

Implication

No change to clinical practice; challenges prior ANGPTL4 macrophage research and leaves its metabolic role open.

Abstract

No abstract yet. The journal hasn't published one we can show.

Synapse visual summary of this paper

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Shizhen Ding (2026) studied this question.

synapsesocial.com/papers/69a76571badf0bb9e87d91c3 https://doi.org/10.62347/ramu3850

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progressionpreclinical · 2016 · 114 citations
2Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic micepreclinical · 2019 · 50 citations
3Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Developmentpreclinical · 2013 · 102 citations
4Feeding Angptl4−/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascitespreclinical · 2017 · 34 citations
5Angiopoietin‐like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cellspreclinical · 2020 · 15 citations

More related papers

Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice2021
Deficiency of angiopoietin‐like 4 enhances <scp>CD8</scp><sup>+</sup> T cell bioactivity via metabolic reprogramming for impairing tumour progression2023
Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice2011

More from American Journal of Cancer Research

Risk factors for cardiac dysfunction caused by anthracycline drugs in the treatment of lymphoma and the early monitoring value of three-dimensional echocardiographyThu,
STAC3 as a poor prognostic biomarker in renal clear cell carcinoma: relationship with immune infiltration: Am J Cancer Res. 2024; 14(7): 3294-3316Thu,