Endometrial microbiota-dimethylglycine-Treg cell axis affects endometrial receptivity in recurrent implantation failure

Key Points

• Endometrial receptivity is significantly influenced by the interaction between microbiota and Treg cells.
• The specific role of dimethylglycine in mediating this relationship is crucial for understanding implantation failure.
• Observational analysis examined endometrial samples in patients experiencing repeated implantation failure.
• Understanding this axis may suggest new therapeutic strategies to improve pregnancy outcomes in affected individuals.