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Median Raphe projection into the dorsal dentate gyrus modulates anxiety behavior and coping with learning under stress | Synapse
March 3, 2026
Open Access
Median Raphe projection into the dorsal dentate gyrus modulates anxiety behavior and coping with learning under stress
JQ
J. Quan
MK
M. Kriebel
RA
R. Anunu
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Key Points
Anxiety behavior can be significantly influenced by the median raphe projection to the dorsal dentate gyrus, enhancing coping mechanisms.
Key evidence shows that altered projections impact learning processes during stressful conditions, possibly improving behavioral outcomes.
This analysis utilized neuroanatomical mapping to assess connections between the median raphe and dorsal dentate gyrus under varying stress levels.
Findings indicate the need for further exploration into how these neural pathways can be targeted for better stress management and anxiety treatments.
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Quan et al. (Mon,) studied this question.
synapsesocial.com/papers/69a76639badf0bb9e87dc344
https://doi.org/https://doi.org/10.1038/s41598-026-38004-w
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