Muscle-specific transcriptomic and metabolomic signatures reveal heterogeneous aging trajectories and altered intercellular communication in male murine skeletal muscle
Key Points
Aging trajectories reveal distinct patterns in skeletal muscle, impacting overall functionality and health.
Key metrics of transcriptomic and metabolomic profiles show variations linked to age in 5 distinct markers.
Observational analysis of murine skeletal muscle examines transcriptomic and metabolomic changes over time.
Findings highlight the complexity of aging, indicating that intercellular communication may be significantly altered.
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Muscle-specific transcriptomic and metabolomic signatures reveal heterogeneous aging trajectories and altered intercellular communication in male murine skeletal muscle | Synapse