The impact of symptom severity and interpersonal problems in psychotherapy for depression with or without comorbid personality disorders: a sub-analysis of a randomised clinical trial

Key Points

• Symptom severity plays a crucial role in psychotherapy outcomes for depression.
• A significant metric shows different responses based on comorbid personality disorders.
• Randomised clinical trial analysis indicates the complexity of treating depression with personality disorders.
• Implications suggest the need for tailored approaches in psychotherapy for individuals with varying symptom profiles.