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February 1, 2026Cirugía Española (English Edition)

Impact of bariatric surgery on the gut microbiota and metabolomic profile of the enterohepatic axis in an experimental model of obesity

Elisabet Homs Margarida Vives Helena Torrell Daniel Del Castillo Antonio Sánchez Fátima Sabench

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Key Points

Bariatric surgery significantly alters the gut microbiota composition and metabolomic profiles.
Key findings highlight shifts in specific microbial populations following surgical intervention.
Experimental analysis reveals changes in the enterohepatic axis related to obesity models.
These findings suggest that altering gut microbiota may lead to improved metabolic outcomes in obesity.

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Implication

Experimental model shows how bariatric surgery alters gut microbiota and metabolomic profiles, indicating potential metabolic benefits.

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Cite This Study

Homs et al. (2026) studied this question.

synapsesocial.com/papers/69a76797badf0bb9e87e18af https://doi.org/10.1016/j.cireng.2026.800297

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Short-Chain Fatty Acids—A Product of the Microbiome and Its Participation in Two-Way Communication on the Microbiome-Host Mammal LineOriginal Research · 2023 · 150 citations
2Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric SurgeryCase-Control Study · 2016 · 88 citations
3Gut Microbiome and Metabolites in Patients with NAFLD and after Bariatric Surgery: A Comprehensive ReviewReview · 2021 · 35 citations
4Length of biliopancreatic limb in Roux-en-Y gastric bypass and its impact on post-operative outcomes in metabolic and obesity surgery—systematic review and meta-analysismeta-analysis · 2022 · 35 citations
5The Art of Sleeve Gastrectomy2024 · 19 citations

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