Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 4, 2022International Journal of ObesityOpen Access

Length of biliopancreatic limb in Roux-en-Y gastric bypass and its impact on post-operative outcomes in metabolic and obesity surgery—systematic review and meta-analysis

View Full Paper
Ask AI
Bookmark
Share

Why the study?

No consensus exists on the optimal design of Roux-en-Y gastric bypass, with various bypassed small bowel limb lengths being used by bariatric surgeons.

Does a long biliopancreatic limb compared to a short biliopancreatic limb in Roux-en-Y gastric bypass improve weight loss and resolution of metabolic comorbidities in patients with obesity?

Comparison

Short vs long biliopancreatic limb in Roux-en-Y gastric bypass

Design

Systematic review and meta-analysis of randomised controlled trials

Follow-up

12-72 months

Authors

AKAnna KamockaMedical University of BiałystokSCSwathikan ChidambaramImperial College LondonSESimon ErridgeCURE International UK

Discussion

Loading...

Member takes

Implication

Altering BPL length yields no consistent RYGB outcome benefit; leaves open optimal limb configuration for prospective trials.

Structured PICO

Does a long biliopancreatic limb compared to a short biliopancreatic limb in Roux-en-Y gastric bypass improve weight loss and resolution of metabolic comorbidities in patients with obesity?

P
Population
Patients with obesity and associated comorbidities undergoing Roux-en-Y gastric bypass (10 RCTs)
I
Intervention
Long biliopancreatic limb (BPL) in Roux-en-Y gastric bypass
C
Comparator
Short biliopancreatic limb (BPL) in Roux-en-Y gastric bypass
O
Outcome
Reduction in weight, body mass index (BMI), and resolution of metabolic comorbidities (type 2 diabetes mellitus, hypertension, dyslipidaemia) and complicationssurrogate

Alteration of the biliopancreatic limb length in Roux-en-Y gastric bypass does not significantly affect long-term weight loss or resolution of metabolic comorbidities.

Cite This Study

Kamocka et al. (2022) studied this question.

synapsesocial.com/papers/6a869bd5846a19e9b02aad91https://doi.org/10.1038/s41366-022-01186-0
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Weight Loss and Metabolic Improvement in Morbidly Obese Subjects Implanted for 1 Year With an Endoscopic Duodenal-Jejunal Bypass Liner2012 · 113 citations
  2. 2Type 2 diabetes remission 2 years post Roux‐en‐Y gastric bypass and sleeve gastrectomy: the role of the weight loss and comparison of DiaRem and DiaBetter scores2017 · 102 citations
  3. 3The Effect of Standard Versus Longer Intestinal Bypass on GLP-1 Regulation and Glucose Metabolism in Patients With Type 2 Diabetes Undergoing Roux-en-Y Gastric Bypass: The Long-Limb Study2020 · 35 citations
  4. 4Clinical and Patient-Centered Outcomes in Obese Patients With Type 2 Diabetes 3 Years After Randomization to Roux-en-Y Gastric Bypass Surgery Versus Intensive Lifestyle Management: The SLIMM-T2D Study2018 · 138 citations