Key result
Long biliopancreatic limb Roux-en-Y gastric bypass did not significantly improve percentage of excess weight loss at 24 months compared to short limb bypass (86.4% vs 83.4%, p=0.285).
Why the study?
Although studies reported superior weight reduction with long biliopancreatic limb in Roux-en-Y gastric bypass, no recommendations regarding limb lengths exist.
Does a long biliopancreatic limb compared to a short biliopancreatic limb improve weight loss and comorbidity resolution in patients undergoing Roux-en-Y gastric bypass?
Cohort (n=308)
No
Does a long biliopancreatic limb compared to a short biliopancreatic limb improve weight loss and comorbidity resolution in patients undergoing Roux-en-Y gastric bypass?
Absolute Event Rate: 86.4% vs 83.4%
p-value: p=0.285
In patients undergoing Roux-en-Y gastric bypass, a long biliopancreatic limb (100 cm) did not significantly improve weight loss or resolution of obesity-related comorbidities at 24 months compared to a short limb (50 cm).
Long BPL RYGB was not associated with superior weight loss; leaves open optimal limb length in randomized trials.
PURPOSE: Although recent studies reported superior weight reduction in patients undergoing Roux-en-Y gastric bypass (RYGB) with long biliopancreatic limb (BPL), no recommendation regarding limb lengths exists. This study compares weight loss and resolution of obesity-related comorbidities in patients undergoing RYGB with either long or short BPL. METHODS: A retrospective data search from medical records was performed. A total of 308 patients underwent laparoscopic RYGB with a BPL length of either 100 cm or 50 cm. Data was analyzed before and after propensity score matching. RESULTS: No statistically significant difference in weight reduction between long and short BPL RYGB in terms of percentage of excess weight loss (%EWL) (86.4 ± 24.5 vs. 83.4 ± 21.4, p = 0.285) and percentage of total weight loss (%TWL) (32.4 ± 8.4 vs. 33.0 ± 8.3, p = 0.543) was found 24 months after surgery. Propensity score-matched analysis did not show any statistically significant difference between groups in both %EWL and %TWL. No significant difference between long and short BPL RYGB in the resolution of obesity-related comorbidities was noted 24 months after surgery. CONCLUSION: Weight loss and resolution of obesity-related comorbidities were not significantly different between long and short BPL RYGB 24 months after surgery.
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Eckharter et al. (2022) conducted a cohort in Obesity (n=308). Long biliopancreatic limb (LBPL) Roux-en-Y gastric bypass vs. Short biliopancreatic limb (SBPL) Roux-en-Y gastric bypass (50 cm) was evaluated on Percentage of excess weight loss (%EWL) at 24 months (p=0.285). Long biliopancreatic limb Roux-en-Y gastric bypass did not significantly improve percentage of excess weight loss at 24 months compared to short limb bypass (86.4% vs 83.4%, p=0.285).
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