Syntheses, characterization, computational studies, DNA/protein binding, and assessment of antimicrobial potency of new Zinc(II) dithiocarbamates

Key Points

• Antimicrobial potency was significantly enhanced against several strains, showcasing their effectiveness.
• Key metrics indicate a minimum inhibitory concentration of 1.5 µM against Escherichia coli and Staphylococcus aureus.
• Characterization involved spectroscopy and crystallography methods to confirm molecular structure and binding sites.
• These compounds may offer novel therapeutic agents, though clinical application needs further exploration.